Higher Doses of Resveratrol Can Hamper Regeneration and Repair of Muscles: Study

Higher Doses of Resveratrol Can Hamper Regeneration and Repair of Muscles: Study

Researchers through a recently conducted study revealed that resveratrol, an ingredient which is found in chocolate and red wine, and is said to have anti-ageing properties, can actually hamper the regeneration and repair of muscles in higher doses.

Resveratrol is widely sold in supplements and is said to have some powerful antioxidant effects and ability to fight diseases like heart disease, cancer and Alzheimer's.

Scientists through their recent study have found that resveratrol's influence on muscle regeneration could be both good and bad, depending on the concentration used.

The researchers, whose findings appear in the journal Scientific Reports, conducted experiments in the laboratory using muscle cells.

Researchers tested the cycle of muscle regeneration that gets started with the activation of muscle precursors called 'satellite' cells.

Laboratory tests conducted by scientists showed that small doses of the ingredient supported cells in the repair process but its higher doses had the opposite effect on cells.

Lead researcher Dr. Hans Degens, from Manchester Metropolitan University (MMU), said stronger muscles and the ability of the muscle to repair damage are important for health, especially in older age.

Therefore, they tried to find out if resveratrol was actually contributing in the repair of muscle and promoting in reducing oxidative stress.

Researchers found that at low doses, resveratrol do play a role in repairing of muscles. But if the dose is higher, it does not slow down ageing from oxidative stress and even hampers the repair cycle of muscles.

"The results showed that the effects are dependent on the dose and it is unclear from the equivocal results if drinking wine or eating chocolate would have anti-ageing properties and repair muscle or the opposite", Degens said.


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