Depression and Brain Inflammation Might be Linked: Study

Depression and Brain Inflammation Might be Linked: Study

The Canadian scientists have made a big breakthrough in depression research with an all new study that has found inflammation deep in the brains of the patients suffering from the illness.

Although this research is in its early stages, it has still provided scientists with a possible alternative cause for the disease. This research also provides an explanation why around 30 to 50% of patients with depression don't respond to medication at all.

For this research, the researchers from the Centre for Addiction and Mental Health (CAMH) in Toronto compared the brain scans of 20 patients with clinical depression to the brains scans of 20 people without depression. They found that all the people with depression had an average 30% more inflammation in their brains. They found that the greater the inflammation, the more severe the patient's symptoms will be.

The findings so generated by this research are indeed significant as they raise the question of whether getting rid of the inflammation would eliminate depression altogether in such patients.

All the findings related to this study were published on Wednesday in the journal JAMA Psychiatry.

In an interview to CTV News, researcher Dr. Jeffrey Meyer of CAMH said, "Inflammation is the body's immune response to infection or trauma, and is implicated in a range of illnesses. Statistics show that people with certain inflammatory disease, such as lupus, are several times more likely to develop clinical depression".

Meyer added that one theory behind the inflammation found deep in the brains of patients with clinical depression is that they are exposed to an infection or trauma and their brain has not yet "cooled off" from the experience.


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